Sex difference in antithrombotic effect of aspirin.
نویسندگان
چکیده
منابع مشابه
Sex difference in antithrombotic effect of aspirin.
A number of clinical trials suggest that the antithrombotic effect of aspirin is limited to men. To test the possibility that this is due to a sex difference in the inhibitory effect of aspirin on platelet behavior, we studied whole-blood platelet aggregation in men and women and in male patients with carcinoma of the prostate receiving hormone therapy. The in vitro inhibitory effect of aspirin...
متن کاملThe Mechanism of the Antithrombotic Effect of Aspirin
“D OES ASPIRIN PREVENT heart attacks?” The question is asked by both patients and physicians who wonder how a pill for headaches could influence a lethal vascular event. Today, a wealth of evidence shows that aspirin does, indeed, prevent heart attacks and related thrombotic disorders such as strokes.’ Performed over more than two decades, the pertinent studies range from clinical epidemiology ...
متن کاملThe antithrombotic profile of aspirin. Aspirin resistance, or simply failure?
Introduction Cyclooxygenase-1 [COX-1, prostaglandin synthase] catalyses the transformation of arachidonic acid to the unstable intermediate prostaglandin PGH2. Subsequently, thromboxane synthase acts on PGH2 to form TXA2, a transient biological product that induces platelet aggregation and is a powerful vasoconstrictor. Aspirin acts primarily by interfering with the biosynthesis of cyclic prost...
متن کاملSex related differences in platelet function: the effect of aspirin.
There is evidence from clinical studies and animal experiments that aspirin has a greater antithrombotic activity in males compared to females. We investigated platelet function in vitro and in vivo in rabbits before and after the administration of a dose of aspirin (5 mg/kg) which inhibited collagen stimulated thromboxane B2 generation. Infusion of collagen into untreated animals resulted in a...
متن کاملthe effect of the record infancy in crimilly acts of guilties (in karaj city)
چکیده یکی از مهمترین دغدغه های بزرگ جوامع بشری، از دیر باز تا کنون که ذهن پژوهشگران و متخصصان بهداشت روانی و اجتماعی و دولتها رابه خود مشغول داشته، مسأله ی بزهکاری می باشد. شناخت کامل پدیده ی بزهکاری و بزهکار، علل وعوامل سقوط یک انسان، چگونگی درمان وی و درنهایت پیشگیری ازبزهکاری ودریک کلام سالم سازی یک جامعه، رسالت عظیم، انسانی ومقدسی می باشد که با بررسی شخصیت مجرم یعنی[ انسانی که تحت شرای...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Stroke
سال: 1989
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.20.1.34